An article in a Diabetes newsletter made me sit up and take notice, as we've been hearing just the opposite sometimes - that artificial sweeteners can cause weight gain of all things! What to believe nowadays....?!! My experience tells me that sugar makes me fat and Splenda helps me stay away from sugar which makes me fat. However, too many desserts with Splenda will still put weight on me, though not as quickly as sugary, white flour products do - everything in moderation, especially when actually dieting to lose weight.